Medicinal and Aromatic Plants Research Institute and Traditional Medicine

 

 

 

Establishment:

In 1972 Medicinal and Aromatic Research Unit was established by the National Council for Research. During 1983, this unit was upgraded to become an institute affiliated to the Council of Medical Research. In 1992 it became a fully-fledged research institute.

Objectives:

  • Collection and documentation of the experience of Sudanese nation and its inherited knowledge in herbal remedies and other traditional medical practices.
  • Conduction of agricultural research related to the Sudanese medicinal and aromatic plants with view to their development. In addition to acclimatization of foreign varieties, and opening of new international market to support the national economy.
  • Establishment of herbarium of medicinal and aromatic plants in addition to a museum for other traditional medical practices.
  • Conduction of experiments on medicinal plants with view of extracting medicines to achieve self-reliance.
  • Extraction of flavoring agents for food and cosmetics industry.
  • Strengthening of scientific relations between the institute compartments and the local industrial institution and organization.
  • Collection and conservation of endangered and stinct Sudanese genetic resources.
  • Promotion and supervision of post-graduate studies; higher diploma, M.Sc, and Ph.D.
  • Encouragement of perfumery industries based on Sudanese aromatic plants or foreign adopted ones.

Departments of MAPRI:

Research in the institute is undertaken by seven major departments of which;

Department of Phytochemistry and Taxonomy:

Objectives:

  • Preparation of an Atlas of Sudanese Medicinal, Aromatic, and Poisonous Plants "Materia Medica".
  • Isolation and structure elucidation of pharmaceutically interesting plant constituents, as drugs or precursors for drug synthesis and for quality control for finished products.
  • Preparation of Monographs for Standardization of Sudanese Medicinal Plant "as a Nucleus for Sudanese Herbal Pharmacopoeia".

Department of Parasitiology and Microbiology:

Objectives:

  • Discovery of antibacterial and antiparasitical drugs from plant origin.
  • Discovery of antithelementic drugs from plant origin.
  • Discovery of antimalarial drugs from plant origin.
  • Application of Medicinal plants in the control of disease vectors.
  • Study of the immune modulating activities of the medicinal plants.
  • Discovery of antivirus drugs from plant origin.

Department of Pharmacology and Toxicology:

Objectives:

  • To study the effect of plant extracts in its crude, semi-purified or pure form on intact animals or isolated organs or tissues and to evaluate their use in traditional medicine and to screen their pharmacological activities. these experiments are carried out in parallel with fractionation process of active principals(s).
  • To study the side effects of plant extracts or pure active constituent(s) by conducting toxicological studies to ensure the safety of the drug and to determine the lethal dose that kills 50% of animals studied (LD50).

Department of Agro technology:        

Objectives:

  • Protection of Sudanese Medicinal and Aromatic plants from extinction through agricultural research leading to plantation, conservation and production of certified seeds.
  • Development of new varieties of Sudanese plants of high quality for production and competitiveness in worldwide markets.
  • Acclimatization of some economically important internationally or globally activation of potentially know Medicinal and Aromatic plants to the climate of Sudan.
  • Search for selection of the suitable package of technique for production of selected medicinal plants and issuing of extensional pamphlets.
  • Development and application of biotechnology in production, improvement, and conservation of medicinal and aromatic plants.

Medical Biochemistry Research Unit:

The Medical Biochemistry Research Unit (MBRU) is a preclinical, basic biochemistry research division of Medicinal and Aromatic Plants Research Institute. The research activities of MBRU fall into three major areas:

  • Enzymology and enzyme inhibition research
  • Antioxidant discovery research
  • Structural computational chemistry research.

The enzyme inhibition studies target the medically important enzymes involved in various diseases with special emphasis on the endemic diseases in Sudan.

Abnormal rise in the intracellular oxidants levels may ultimately result in the development of several pathological disorders including cancers, inflammation, neurodegeneration, Parkinson's disease, atherosclerosis and pre-mature aging. Our research on antioxidants is extensively focused in discovering the antioxidant properties of natural/synthetic compound, and the investigating the mechanism of antioxidants. Structural computational chemistry is also used to understand ligand receptor recognition. Our research group uses some of the most widely used algorithm for docking of flexible ligands such as Auto dock and Dock soft wares.

 

Collaborations with international organizations and institutes: 

 MAPRI has wide regional & international collaborative network that includes: (2) African Network for Drugs and Diagnostics Innovation (ANDI), (2) COST (European Cooperation in Science and Technology) CMST Action CM0801 “New Drugs for Neglected Diseases”;(3) International Center for Chemical and Biological Sciences (Pakistan) (4) Natural Product Research Network for Eastern and Central Africa (NAPRECA), and (5) Chinese Academy of Sciences/Institute of Botany

 

      Address:

 

P. O. Box 1304, Khartoum, SUDAN

Director: Prof. Atif Abdelrahman Elagib Associate Professor

Tel:    (+249-183) 773771, 786086

Fax:   (+ 249-183) 773771

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.

 

 

 

 

  • Last Modified: Monday 30 November 2015, 01:05:25.

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