Tropical Medicine Research Institute (TMRI)

Establishment:

The Tropical Medicine Research Institute (TMRI) was established in 1972.

Background:

The Tropical Medicine Research Institute (TMRI) was established in 1972.The main activities of the TMRI are to undertake applied research programmes on the transmission and control of parasitic diseases. Improve the diagnostic methodology and implement new finer tools for the control of endemic diseases in the Sudan.

Since its initiation, the research activities have been designed and directed towards applied field research in tropical diseases. It operates as a research and training institution for endemic tropical diseases in the Sudan, with special emphasis on parasitic diseases. The institute is working in close collaborating with the Federal and States Ministries of Health, universities, research institutes and with international agencies, research centers and laboratories. The majority of the research projects are of applied nature directed towards the control of the endemic tropical parasitic diseases. Special emphasis has been given to malaria, trypanosomiasis, leishmaniasis and schistosomiasis.

The introduction of the new technologies in the study of epidemiology, diagnosis and treatment strategies was given a high priority in research. Cancer research has started at TMRI in response to its emergence as a public health problem in the Sudan .The staff is involved mainly on the supervision of post-graduate students working in the different research projects at TMRI. During 2005, the Sudan Academy for Sciences (SAS) was established by MOST as a specialized university for postgraduate studies. The responsibilities of the Tropical Medicine programmes at SAS are entrusted to TMRI. The institute is running two programmes for M. Sc. degree, immunology and microbiology. Building the capacity of TMRI and rehabilitating the laboratories has been main objective during 2005.The institute was able to recruit young scientists and new graduates to work in the research projects. The laboratories were provided with new equipment. Beside the regular government budget provided by NCR, MOST and Federal Ministry of Finance, the institute is receiving financial and technical support from different international agencies that support research and development.

Objectives:

  1. Conduct scientific and applied research in different tropical diseases. 

2. Qualify and train the researchers and assisting staff of TMRI.

3. Train medical and health personnel on advance novel methods for diagnosis and control of tropical diseases.

4. Consolidate cooperation and experiences with national and international health institutions and research organizations.

5. Motivation for scientific excellence and innovation.

6. Provision of scientific consultation and advice to governmental institutions and private sector in the field of specialization.

7. Publication and documentation of research achievements and outcomes in national and international journals and periodicals.

 8. Participation and organization of national and international conferences that reflect the scientific research quality.

Departments:

TMRI composed of five departments

A. Epidemiology:

The main objectives of the department are to study the distribution and determinants of the spread of tropical diseases in human population to enable control and prevention, to identify, develop and evaluate innovative methods of disease control, and to conduct training courses on bio-statistics, research methodology and molecular epidemiology.

B. Microbiology:

The department of microbiology is working mainly on pathogenic bacteria. The research is focused on evaluation of new modern techniques for diagnosis of tuberculosis, characterization of bacterial infections, zoonosis and antibiotic resistance. The research carried out in the department is sponsored by NCR.

C. Parasitology and Medical Entomology:

The main objectives of the department are to conduct research on vectors’ biology and vectors transmitting endemic parasitic diseases with emphasis on: Schistosomiasis, Trypanosomiasis, Leishmaniasis, Malaria and Filariasis; and to carry out research on non-infectious and zoonotic diseases.

D. Immunology and Biomedical Technologies:

The main objectives of the department are to carry out research on immunological aspects of the tropical parasitological diseases (Malaria, Schistosomiasis, Leishmanisis, Onchocercasis and Trypanosomiasis) with emphasis on the human response to infection; to conduct research on various types of cancer; to transfer knowledge of new technologies including molecular biology techniques for diagnosis and for studying the moleculo-biological features of infectious diseases using new technologies and to strengthen the collaboration with other national and international research institutions in the fields of biotechnology and immunology.

E. Clinical Studies:

The main objectives of the department are to carry out researches on clinical studies for the patients whom are hospitalized at Tropical Hospital in Omdurman whom are suffering from tropical diseases like (Malaria, Schistosomiasis, Leishmanisis, Onchocercasis, Trypanosomiasis and any other related diseases).

Ongoing Research Projects:

  • Feasibility Study of the Sterile Insect Technique for Elimination of the Malaria Vector Anopheles arabiensis in Northern State, Sudan (RAF 5/052)
  • Mass rearing and pre-release biology of Anopheles arabiensis, IAEA (RC no. 3293, Regular Budget Fund).
  • Control of malaria by administration of artemisinin based combination therapy at the end of the dry season in an area of seasonal transmission in eastern Sudan (SUD 6/025).
  • Intermittent Preventive Treatment (IPT) for the control of malaria in children.
  • The Role of Human Haptoglobin in Modulation of Falciparum Malaria Infection.
  • Establishment of malaria parasite bank.
  • Establishment of Leishmania parasite database.
  • Use of a single-step PCR method for malaria parasite detection.
  • Control of leishmaniasis in Sudan; The role of Post-Kala-azar Dermal Leishmaniasis in transmission of Leishmania donovani inside villages in a focus of visceral leishmaniasis in Eastern Sudan”. (TDR/EMRO: ID SGS08/88)
  •  Detection and identification of sand fly vector(s) and reservoir host(s) in an emerging focus of visceral leishmaniasis in the White Nile State, Sudan (TDR/EMRO: SGS08/179).
  •  Studies on mating behaviour of male Anopheles arabiensis Patton(Diptera Culicidae) in Dongola, Northern Sudan (RC-14871/R0).
  •  Epidemiology of Human Babesiosis Central Sudan.
  • Building capacity for HAT clinical trials in Sudan, funded by DNDi/EU.

 

Technologies produced:                       

Training Facilities:

Several courses and training take place at the (TMRI) institute that include

  • Molecular training
  • Entomological training
  • Biostatistics & SPSS Training

Societal Services:

  • Department of Immunology and Biotechnology offers community services in diagnosing, treatment and follow up to onchocerciasis patients coming from remote areas.
  • Department of Epidemiology provides diagnostic facilities and treatment for malaria and other endemic diseases in Gedarif and Northern States, and Schistosomiasis patients in Gezira. It also provides PCR diagnosis for the four species of malaria parasite to patients refered from the hospitals and private clinics.
  • Department of Vector and Biomedical Studies provides diagnostic facilities for sleeping sickness and toxoplasmosis in its reference laboratory.

 

Address:

Meknimer Street P.O.Box 2404 Khartoum Sudan

Director: Prof. Awatif Ahmed Mohamed A. Siribel

Tel:    (+249-183) ) 773771, 786086.

Fax:   (+ 249-183) 773771

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

  • Last Modified: Monday 30 November 2015, 01:05:25.

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